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New research finds that many people currently taking statins to lower cholesterol may not actually need this medication. An analysis, published in JAMA Internal Medicine , investigates how statin ...
Using PREVENT to calculate the 10-year risk for developing heart disease, the researchers determined that some 40% fewer people would have met the criteria for a statin prescription.
According to researchers, standard statin therapy normally results in a 35-45% reduction in LDL cholesterol, while higher-intensity treatment lowers LDL cholesterol by 45% or more. Lifetime statin ...
In observational studies 10–15% of people who take statins experience muscle problems; in most cases these consist of muscle pain. [6] These rates, which are much higher than those seen in randomized clinical trials [74] have been the topic of extensive debate and discussion. [34] [86]
Conversely, these antibodies are absent in people who take statin medications but do not have myopathy. Thus, the presence of anti-HMG CoA reductase antibodies in someone who uses a statin and has myopathy strongly supports the diagnosis. [3] CK levels increase to 10-100 times above normal (2000–20,000 IU/L) in more than 90% of cases.
These guidelines recommend statin therapy for adults between forty and seventy-five who have diabetes, high cholesterol levels, or an estimated 10-year atherosclerotic cardiovascular disease risk ...