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The fluid bathes the tissues as interstitial fluid, collecting waste products, bacteria, and damaged cells, and then drains as lymph into the lymphatic capillaries and lymphatic vessels. These vessels carry the lymph throughout the body, passing through numerous lymph nodes which filter out unwanted materials such as bacteria and damaged cells.
At the origin of the fluid-return process, interstitial fluid—the fluid between the cells in all body tissues [2] —enters the lymph capillaries. This lymphatic fluid is then transported via progressively larger lymphatic vessels through lymph nodes, where substances are removed by tissue lymphocytes and circulating lymphocytes are added to ...
Upon entering the lumen of a lymphatic capillary, the collected fluid is known as lymph. Each lymphatic capillary carries lymph into a lymphatic vessel, which in turn connects to a lymph node, a small bean-shaped gland that filters and monitors the lymphatic fluid for infections. [1] Lymph is ultimately returned to the venous circulation.
The lymph percolates through the lymph node tissue and exits via an efferent lymph vessel. An efferent lymph vessel may directly drain into one of the (right or thoracic) lymph ducts, or may empty into another lymph node as its afferent lymph vessel. [6] Both the lymph ducts return the lymph to the blood stream by emptying into the subclavian veins
The tissue fluid is entering the blind ends of lymph capillaries (shown as deep green arrows). The arterial blood plasma, interstitial fluid and lymph interact at the level of the blood capillaries. The capillaries are permeable and water can move freely in and out.
Fluid shifts occur when the body's fluids move between the fluid compartments. Physiologically, this occurs by a combination of hydrostatic pressure gradients and osmotic pressure gradients. Water will move from one space into the next passively across a semi permeable membrane until the hydrostatic and osmotic pressure gradients balance each ...
The fluid spaces communicate with draining lymph nodes, although they do not have lining cells or structures of lymphatic channels. [7] Interstitial fluid entering the lymphatic system becomes lymph, which is transported through lymphatic vessels until it empties into the microcirculation and the venous system. [4]
Lymphatic vessels carry lymph, a colorless, watery fluid originating from interstitial fluid (fluid in the tissues) which is squeezed out of the blood vessels. The lymphatic system transports infection-fighting cells called lymphocytes , is involved in the removal of foreign matter and cell debris by phagocytes and is part of the body's immune ...