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The U.S. Food and Drug Administration (FDA) recently approved adding to Wegovy's label that the drug can also reduce the risk of heart events by 20% in people with obesity , for example.
The most common side effects of these drugs that led to withdrawals were mental disturbances, cardiac side effects, and drug abuse or drug dependence. Deaths were associated with seven products. [84] Ephedra was removed from the US market in 2004 over concerns that it raises blood pressure and could lead to strokes and death. [85]
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.
The blockbuster medications have been hailed as wonder drugs for their profound effects on diabetes and weight loss, but a growing number of doctors are concerned that the medications are ...
People with two copies of the FTO gene (fat mass and obesity associated gene) have been found on average to weigh 3–4 kg more and have a 1.67-fold greater risk of obesity compared with those without the risk allele. [140] The differences in BMI between people that are due to genetics varies depending on the population examined from 6% to 85% ...
Mild calorie restriction may be beneficial for pregnant women to reduce weight gain (without weight loss) and reduce perinatal risks for both the mother and child. [11] [12] For overweight or obese individuals, calorie restriction may improve health through weight loss, although a gradual weight regain of 1–2 kg (2.2–4.4 lb) per year may occur.
Research suggests you need a 500–750-calorie deficit daily (meaning you burn 500 more calories daily than you consume) to experience meaningful weight loss on Mounjaro.
This train of thought can then be expanded to compare the danger of drug use to many other recreational activities. When this comparison is made you will find that drugs like LSD and MDMA have less harmful risk associated with them that many other recreational activities like sports, ATVing, and drinking.