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  2. Eisenmenger syndrome - Wikipedia

    en.wikipedia.org/wiki/Eisenmenger_syndrome

    Eisenmenger syndrome or Eisenmenger's syndrome is defined as the process in which a long-standing left-to-right cardiac shunt caused by a congenital heart defect (typically by a ventricular septal defect, atrial septal defect, or less commonly, patent ductus arteriosus) causes pulmonary hypertension [1] [2] and eventual reversal of the shunt into a cyanotic right-to-left shunt.

  3. Right-to-left shunt - Wikipedia

    en.wikipedia.org/wiki/Right-to-left_shunt

    An uncorrected left-to-right shunt can progress to a right-to-left shunt; this process is termed Eisenmenger syndrome. [3] This is seen in Ventricular septal defect, Atrial septal defect, and patent ductus arteriosus, and can manifest as late as adult life. This switch in blood flow direction is precipitated by pulmonary hypertension due to ...

  4. Persistent fetal circulation - Wikipedia

    en.wikipedia.org/wiki/Persistent_fetal_circulation

    Other echocardiographic findings in PPHN include right ventricular hypertrophy, deviation of the ventricular septum, tricuspid regurgitation, and shunting at the patent foramen ovale. [ 3 ] Other clinical signs that may signify PPHN are respiratory distress, partial pressure of oxygen greater than 100 mg and elevated partial pressure of carbon ...

  5. Cardiac shunt - Wikipedia

    en.wikipedia.org/wiki/Cardiac_shunt

    Atrial septal defect with left-to-right shunt. The left and right sides of the heart are named from a dorsal view, i.e., looking at the heart from the back or from the perspective of the person whose heart it is. There are four chambers in a heart: an atrium (upper) and a ventricle (lower) on both the left and right sides. [1]

  6. Pulmonary shunt - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_shunt

    A pulmonary shunt is the passage of deoxygenated blood from the right side of the heart to the left without participation in gas exchange in the pulmonary capillaries. It is a pathological condition that results when the alveoli of parts of the lungs are perfused with blood as normal, but ventilation (the supply of air) fails to supply the perfused region.

  7. Pulmonary hypertension - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_hypertension

    Persistent pulmonary hypertension of the newborn occurs when the circulatory system of a newborn baby fails to adapt to life outside the womb; it is characterized by high resistance to blood flow through the lungs, right-to-left cardiac shunting and severe hypoxemia. [15]

  8. Alveolar gas equation - Wikipedia

    en.wikipedia.org/wiki/Alveolar_gas_equation

    The partial pressure of oxygen (pO 2) in the pulmonary alveoli is required to calculate both the alveolar-arterial gradient of oxygen and the amount of right-to-left cardiac shunt, which are both clinically useful quantities. However, it is not practical to take a sample of gas from the alveoli in order to directly measure the partial pressure ...

  9. Ventilation–perfusion coupling - Wikipedia

    en.wikipedia.org/wiki/Ventilation–perfusion...

    The right-to-left shunt is an abnormal blood circulation that enables deoxygenated blood to pass from the right side to the left side of the heart and skips the lungs. Thus, no oxygenation occurs, and reduced gas exchange results in hypoxemia as fresh oxygen cannot reach the shunted blood. [ 18 ]