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The cell membrane of a cardiac muscle cell has several specialized regions, which may include the intercalated disc, and transverse tubules. The cell membrane is covered by a lamina coat which is approximately 50 nm wide. The laminar coat is separable into two layers; the lamina densa and lamina lucida.
T-tubules (transverse tubules) are extensions of the cell membrane that penetrate into the center of skeletal and cardiac muscle cells.With membranes that contain large concentrations of ion channels, transporters, and pumps, T-tubules permit rapid transmission of the action potential into the cell, and also play an important role in regulating cellular calcium concentration.
The sarcoplasmic reticulum is a network of the tubules that extend throughout muscle cells, wrapping around (but not in direct contact with) the myofibrils (contractile units of the cell). Cardiac and skeletal muscle cells contain structures called transverse tubules (T-tubules), which are extensions of the cell membrane that travel into the ...
Through transmembrane proteins in the plasma membrane, the actin skeleton inside the cell is connected to the basement membrane and the cell's exterior. At each end of the muscle fibre, the surface layer of the sarcolemma fuses with a tendon fibre, and the tendon fibres, in turn, collect into bundles to form the muscle tendons that adhere to ...
The cell membrane has different lipid and protein compositions in distinct types of cells and may have therefore specific names for certain cell types. Sarcolemma in muscle cells: Sarcolemma is the name given to the cell membrane of muscle cells. [46] Although the sarcolemma is similar to other cell membranes, it has other functions that set it ...
A group of muscle stem cells known as myosatellite cells, also satellite cells are found between the basement membrane and the sarcolemma of muscle fibers. These cells are normally quiescent but can be activated by exercise or pathology to provide additional myonuclei for muscle growth or repair.
When these cells are depolarized, the L-type calcium channels open as in smooth muscle. In skeletal muscle, the actual opening of the channel, which is mechanically gated to a calcium-release channel (a.k.a. ryanodine receptor, or RYR) in the sarcoplasmic reticulum (SR), causes opening of the RYR.
The endomysium, meaning within the muscle, is a wispy layer of areolar connective tissue that ensheaths each individual muscle fiber, or muscle cell. [1] [2] [3] It also contains capillaries and nerves. It overlies the muscle fiber's cell membrane: the sarcolemma. Endomysium is the deepest and smallest component of muscle connective tissue.