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Lamotrigine (aka Lamictal) FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition ...
Lamotrigine is metabolized predominantly by glucuronic acid conjugation. Its major metabolite is an inactive 2-n-glucuronide conjugate. [82] Lamotrigine has fewer drug interactions than many anticonvulsant drugs, although pharmacokinetic interactions with carbamazepine, phenytoin and other hepatic enzyme-inducing medications may shorten half ...
Lamictal (lamotrigine) – an anticonvulsant used as a mood stabilizer; Latuda – an atypical antipsychotic; Lexapro (escitalopram) – an antidepressant of the SSRI class; Librium (chlordiazepoxide) – a benzodiazepine used to treat acute alcohol withdrawal; Lithobid, Eskalith – a mood stabilizer
A typical starting dosage is 200 mg per day, taken twice a day in 100 mg doses. The maximum Wellbutrin dosage is 450 mg. Wellbutrin XL is the extended-release version, ranging between 150 mg and ...
Lexapro is one of the most recognizable drug names of our modern era. ... an estimated 14.8 million U.S. adults aged 18 or older experienced at least one major depressive episode over the last ...
[122] [123] [124] For instance, a 2004 U.S. Food and Drug Administration (FDA) analysis of clinical trials on children with major depressive disorder found statistically significant increases of the risks of "possible suicidal ideation and suicidal behavior" by about 80%, and of agitation and hostility by about 130%. [125]
The defined daily dose (DDD) is a statistical measure of drug consumption, defined by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology. It is defined in combination with the ATC Code drug classification system for grouping related drugs.
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50 , meaning "effective dose for 50% of the population".
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