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Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Alpha radiation is a nuclear phenomenon in which a heavy radionuclide emits an energetic alpha particle (consisting of two protons and two neutrons) and transmutes to a different radionuclide. The emitted alpha particle has a range in tissue of only 40-90 microns, which minimizes collateral damage when used for treatment purposes.
For the next 37 years she helped hundreds of cancer patients in the U.S. and worldwide return to healthy lives, as well as educate many more about prevention and treatment of chronic disease. Sackman's yardstick for success was always long-term recovery, i.e., at least 10 years cancer-free.
Anti-cancer psychotherapy – a technique [131] claiming that a "cancer personality" caused cancer, which could be cured through talk therapy (e.g. that of the Simonton Cancer Center, [132] Bernie Siegel's "Exceptional Cancer Patients" (ECaP) or Deepak Chopra). Evidence is lacking that cancer cures sold or promoted by Deepak Chopra have any value.
The Szent-Györgyi Prize for Progress in Cancer Research, established by the NFCR and named in honor of Albert Szent-Györgyi, Nobel Laureate and co-founder of NFCR, has been awarded annually since 2006 to outstanding researchers whose scientific achievements have expanded the understanding of cancer and whose vision has moved cancer research in new directions.
The majority of drugs used in cancer chemotherapy are cytostatic, many via cytotoxicity. A fundamental philosophy of medical oncology , including combination chemotherapy, is that different drugs work through different mechanisms, and that the results of using multiple drugs will be synergistic to some extent.