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The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis is tightly connected to the epidermis by a basement membrane. It also harbours many nerve endings that provide the sense of touch and heat.
The skin (integument) is a composite organ, made up of at least two major layers of tissue: the epidermis and the dermis. [2] The epidermis is the outermost layer, providing the initial barrier to the external environment. It is separated from the dermis by the basement membrane (basal lamina and reticular lamina).
The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils , microfibrils , and elastic fibers , embedded in hyaluronan and proteoglycans . [ 15 ]
An apocrine sweat gland (/ ˈ æ p ə k r ə n,-ˌ k r aɪ n,-ˌ k r iː n /; from Greek apo 'away' and krinein 'to separate') [5] [6] is composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. [7]
Their secretory part is present deep inside the dermis. Eccrine glands are composed of an intraepidermal spiral duct, the "acrosyringium"; a dermal duct, consisting of a straight and coiled portion; and a secretory tubule, coiled deep in the dermis or hypodermis. [7] The eccrine gland opens out through the sweat pore.
The primary function of keratinocytes is the formation of a barrier against environmental damage by heat, UV radiation, dehydration, pathogenic bacteria, fungi, parasites, and viruses.
H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...