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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [ 4 ] [ 5 ] [ 2 ] Symptoms in mild cases include high blood pressure and a fast heart rate ; usually without a fever . [ 2 ]
Similarly to other antidepressants, SNRI medications have been found to cause visual snow syndrome, a condition characterized by visual static, palinopsia (negative after image), nyctalopia (poor vision at night), and photophobia (brighter presentation of lights or highlighted colors). Evidence shows that 8.9% of those taking SNRIs experienced ...
Another example of additive effects for adverse drug reactions is in serotonin toxicity (serotonin syndrome). [29] If medications that cause increased serotonin levels are combined, they can cause serotonin toxicity (though therapeutic doses of one agent that increases serotonin levels can cause serotonin toxicity in certain cases and ...
[17] [73] [111] However, there are a handful of case reports of serotonin syndrome occurring with mirtazapine in combination with serotonergic drugs like selective serotonin reuptake inhibitors, although such reports are very rare, and do not necessarily implicate mirtazapine as causative. [17] [112] [113] [114]
Serotonin syndrome is typically caused by the use of two or more serotonergic drugs, including SSRIs. [118] Serotonin syndrome is a condition that can range from mild (most common) to deadly. Mild symptoms may consist of increased heart rate , fever , shivering, sweating , dilated pupils , myoclonus (intermittent jerking or twitching), as well ...
According to the Mayo Clinic, some of these medications include: Medications that increase dopamine in the brain. Rotigotine (Neupro) and pramipexole (Mirapex) are approved by the FDA for the ...
While safer than general MAOIs, RIMAs still possess significant and potentially serious drug interactions with many common drugs; in particular, they can cause serotonin syndrome or hypertensive crisis when combined with almost any antidepressant or stimulant, common migraine medications, certain herbs, or most cold medicines (including ...
An abortive serotonin syndrome state, in which some but not all of the symptoms of the full serotonin syndrome are present, has been reported with venlafaxine at mid-range dosages (150 mg per day). [45] A case of a patient with serotonin syndrome induced by low-dose venlafaxine (37.5 mg per day) has also been reported. [46]