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An anal fissure is a break or tear in the skin of the anal canal. Anal fissures may be noticed by bright red anal bleeding on toilet paper and undergarments, or sometimes in the toilet. If acute they are painful after defecation , [ 1 ] but with chronic fissures, pain intensity often reduces and becomes cyclical.
[3] [2] It does not usually spread between people. [3] The disease is classified into four types, depending on the infecting organisms. [4] Medical imaging is often helpful to confirm the diagnosis. [4] Necrotizing fasciitis is treated with surgery to remove the infected tissue, and antibiotics. [2] [3] It is considered a surgical emergency.
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Schematic image comparing a skin fissure to an erosion and an ulcer. The surface of the knuckles of a hand with xeroderma, showing skin cracking (generalized skin fissuring). A skin fissure is a cutaneous condition in which there is a linear-like cleavage of skin, sometimes defined as extending into the dermis. [1] It is smaller than a skin ...
An oroantral fistula (OAF) is an epithelialized oroantral communication (OAC), which refers to an abnormal connection between the oral cavity and the antrum. [1] The creation of an OAC is most commonly due to the extraction of a maxillary tooth (typically a maxillary first molar) which is closely related to the antral floor.
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Research into hormones and wound healing has shown estrogen to speed wound healing in elderly humans and in animals that have had their ovaries removed, possibly by preventing excess neutrophils from entering the wound and releasing elastase. [26] Thus the use of estrogen is a future possibility for treating chronic wounds.
Perisylvian syndrome is a rare neurological disease characterized by damage to the sylvian fissure (lateral sulcus), an area in the brain involved in language and speech. . The main symptoms are difficulty chewing and swallowing, low muscle tone in the face and tongue, speech and language development disorders, and epile