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Preventive measures against cSCC include minimizing exposure to ultraviolet radiation and the use of sunscreen. [5] [6] Surgical removal is the typical treatment method, [2] employing simple excision for minor cases or Mohs surgery for more extensive instances. [2] Other options include cryotherapy and radiation therapy. [7]
Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology. [1] CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.
Basal-cell carcinomas are most commonly present on sun-exposed areas of the skin, especially the face. They rarely metastasize and rarely cause death. They are easily treated with surgery or radiation. Squamous-cell skin cancers are also common, but much less common than basal-cell cancers. They metastasize more frequently than BCCs.
Comparing Mohs Surgery Method to smashing an aluminum pie pan How a Mohs Section is flattened with relaxing incisions False negative in standard bread loafing histology: If the pathologist looks only at the margin of the three narrow slices, the many cancerous cells on the discarded margins will be missed.
The success rate of Mohs surgery is comparable to radiation therapy in squamous cell carcinoma, and one should also discuss this before approaching high-risk squamous cell cancers of the ear or lips. Combining these modalities should be considered to increase the cure rate in selective cases, and should also be discussed.
After three years, 57% of those who got chemo and surgery were alive, compared to 51% of those who got chemo, surgery and radiation. The German Research Foundation funded the study. HODGKIN LYMPHOMA