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Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [9]
Atherosclerosis happens when a fatty substance called plaque builds up inside your arteries. There are typically few noticeable symptoms until the situation becomes dire and you experience ...
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
Coronary artery ectasia is characterized by an increased wall stress of the vessel, thinning of the arterial wall which causes progressive dilation and remodelling of the vessel. [2] The permanent dilation of the artery is thought to be mainly caused by inflammation, triggered by disease, chemicals, or physical stress of the vessel. [ 3 ]
Stages of endothelial dysfunction in atherosclerosis of arteries Endothelial dysfunction may be involved in the development of atherosclerosis [ 5 ] [ 6 ] [ 7 ] and may predate vascular pathology. [ 5 ] [ 8 ] Endothelial dysfunction may also lead to increased adherence of monocytes and macrophages , as well as promoting infiltration of low ...
Rupture of the plaque can release atherosclerotic debris or blood clots into the artery. A piece of this material can break off and travel ( embolize ) up through the internal carotid artery into the brain, where it blocks circulation, and can cause death of the brain tissue, a condition referred to as ischemic stroke .
Atherosclerosis is a developmental disease in the large arteries, defined by the accumulation of lipids, macrophages and fibrous materials in the intima. [1] When the endothelial cell of blood vessel is damaged, it loses the ability to regulate itself. [1] It results in inflammation as the macrophages irrupt the vessel wall. [1]
Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. The term atherogenic is used for substances or processes that cause atherosclerosis. Micrograph showing hyaline arteriolosclerosis in the kidney. PAS stain.