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Melzack's recent research at McGill indicates that there are two types of pain, transmitted by two separate sets of pain-signaling pathways in the central nervous system. Sudden, short-term pain, such as the pain of cutting a finger, is transmitted by a group of pathways that Melzack calls the "lateral" system, because they pass through the ...
Wall & Melzack's Textbook of Pain is a medical textbook published by Elsevier. It is named after Patrick David Wall and Ronald Melzack, who introduced the gate control theory into pain research in the 1960s. First released in 1984, the book has been described as "the most comprehensive scientific reference text in the field of pain medicine". [1]
The McGill Pain Questionnaire, also known as McGill Pain Index, is a scale of rating pain developed at McGill University by Melzack and Torgerson in 1971. [1] It is a self-report questionnaire that allows individuals to give their doctor a good description of the quality and intensity of pain that they are experiencing.
In 1968, three years after the introduction of the gate control theory, Ronald Melzack concluded that pain is a multidimensional complex with numerous sensory, affective, cognitive, and evaluative components. Melzack's description has been adapted by the International Association for the Study of Pain in a contemporary definition of pain. [1]
William Kenneth Livingston advanced a summation theory in 1943, proposing that high intensity signals, arriving at the spinal cord from damage to nerve or tissue, set up a reverberating, self-exciting loop of activity in a pool of interneurons, and once a threshold of activity is crossed, these interneurons then activate "transmission" cells ...
The article detailed the various techniques that the pharmaceutical company Insys Therapeutics used to push its highly addictive fentanyl-based painkiller Subsys into the marketplace, including ...
A new understanding of pain perception was ushered in in 1965, with the Gate Theory of Wall and Melzack. [39] Although now considered oversimplified, the theory held that pain transmissions from small nerve fibers can be overridden, or the gate "closed", by competing transmissions along the wider touch nerve fibers.
The neuromatrix theory, initially coined by psychologist Ronald Melzack in the 1990s, proposes that there is an extensive network connecting the thalamus and the cortex, and the cortex and the limbic system. [8]