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The word melanoma has a long history of being used in a broader sense to refer to any melanocytic tumor, typically, but not always malignant, [170] [171] but today the narrower sense referring only to malignant types has become so dominant that benign tumors are usually not called melanomas anymore and the word melanoma is now usually taken to ...
Causes of melanoma. Ultraviolet light exposure from the sun or from tanning beds causes most melanomas. Melanoma may appear at a spot where you have an existing mole. But if an unusual spot shows ...
Melanoma has one of the higher survival rates among cancers, with over 86% of people in the UK and more than 90% in the United States surviving more than 5 years. [ 18 ] [ 19 ] Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases.
Amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin. [1]: 696 [2] They can be pink, red, purple or of normal skin color, and are therefore difficult to diagnose correctly. They can occur anywhere on the body, just as a typical melanoma can.
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
At least one study indicates a cumulative lifetime risk of nearly 100% in individuals who have dysplastic nevi and are members of melanoma kindreds. [citation needed] Roughly 70% of melanomas arise "de novo" on clear skin growth, whereas the rest arise within atypical moles. [14] Those with dysplastic nevi have an elevated risk of melanoma.
Superficial spreading melanoma (SSM) is a type of skin cancer that typically starts as an irregularly edged dark spot typically on sun-exposed part of the body. [ 2 ] [ 3 ] The colour may be variable with dark, light and reddish shades; occasionally no color at all. [ 2 ]
Lentigo maligna is a histopathological variant of melanoma in situ. [6] Lentigo maligna is sometimes classified as a very early melanoma, [7] and sometimes as a precursor to melanoma. [8] When malignant melanocytes from a lentigo maligna have invaded below the epidermis, the condition is termed lentigo maligna melanoma. [2]