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When an EEG shows interictal epileptiform discharges (e.g. sharp waves, spikes, spike-and-wave, etc.) it is confirmatory of epilepsy in nearly all cases (high specificity), however up to 3.5% of the general population may have epileptiform abnormalities in an EEG without ever having had a seizure (low false positive rate) [8] or with a very low ...
This reduction in blood glucose led to double the occurrence of spike-and-wave activity. Similar to the insulin effect, overnight fasting, where blood glucose levels were reduced by 35% also showed this double in occurrence. This model concludes that low glucose levels could be a potential trigger for absence seizures, and could be an ...
EEG-fMRI (short for EEG-correlated fMRI or electroencephalography-correlated functional magnetic resonance imaging) is a multimodal neuroimaging technique whereby EEG and fMRI data are recorded synchronously for the study of electrical brain activity in correlation with haemodynamic changes in brain during the electrical activity, be it normal function or associated with disorders.
A paper published in 2023 showed that burst suppression and epilepsy may share the same ephaptic coupling mechanism. [6] When inhibitory control is sufficiently low, as in the case of certain general anesthetics such as sevoflurane (due to a decrease in the firing of interneurons [7]), electric fields are able to recruit neighboring cells to fire synchronously, in a burst suppression pattern.
Partial epilepsy [14] is the common intractable epilepsy and the partial seizure is difficult to locate.Treatment for such epilepsy is limited to attachment of vagus nerve stimulator. Epilepsy surgery is the cure for partial epilepsy provided that the brain region generating seizure is carefully and accurately removed.
In individuals with idiopathic generalized epilepsy, K-complex induced synchronization can trigger spike-and-wave discharges. This tends to happen most between the shift between waking and NREM, and between NREM and REM sleep. [11] In autosomal dominant nocturnal frontal lobe epilepsy, K-complexes are almost invariably present at the start of ...
Epilepsy, a brain disorder that causes seizures, is one of the most common conditions that affects the brain. According to the Centers for Disease Control and Prevention (CDC), about 3.4 million ...
Traditional classification of the frequency bands, that are associated to different functions/states of the brain and consist of delta, theta, alpha, beta and gamma bands. . Due to the limited capabilities of the early experimental/medical setup to record fast frequencies, for historical reason, all oscillations above 30 Hz were considered as high frequency and were difficult to investigate.