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The level of digoxin for treatment is typically 0.5-2 ng/mL. [8] Since this is a narrow therapeutic index, digoxin overdose can happen. A serum digoxin concentration of 0.5-0.9 ng/mL among those with heart failure is associated with reduced heart failure deaths and hospitalizations. [9]
Other oculotoxic effects of digoxin include generalized blurry vision, as well as seeing a "halo" around each point of light. The latter effect can also be seen in van Gogh's 1889 painting The Starry Night. Evidence of van Gogh's digoxin use is supported by multiple self-portraits that include the foxglove plant, from which digoxin is obtained ...
Digoxin increased the risk of death in women by 23%. There was no difference in the death rate for men in the study. [38] Digoxin is also used as a standard control substance to test for P-glycoprotein inhibition. [39] Digoxin appears to be a peripherally selective drug due to limited brain uptake caused by binding to P-glycoprotein. [40] [41]
The Health Risks of Too Much Belly Fat. ... So, the best way to reduce belly fat is to lose any excess weight. ... Meet the top 20 food influencers on YouTube and Instagram. Food.
"Belly fat, also known as visceral fat, is dangerous because this is the fat that is more often related to negative health consequences." Dr. Ortiz-Pujols explains. Dr. Ortiz-Pujols explains.
Here's the thing about extreme diets, though—as much as you might want to lose 10 pounds in the short-term, you’re not doing yourself any favors over the long-term. Very low-calorie diets can ...