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Kaposi's sarcoma (KS) is a type of cancer that can form masses on the skin, in lymph nodes, in the mouth, or in other organs. [ 4 ] [ 6 ] The skin lesions are usually painless, purple and may be flat or raised.
Micrograph_of_plaque_stage_of_Kaposi's_sarcoma.jpg (665 × 501 pixels, file size: 170 KB, MIME type: image/jpeg) This is a file from the Wikimedia Commons . Information from its description page there is shown below.
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus.It is also called Human herpesvirus 8, or HHV-8 in short. [2] This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients, [3] as well as primary effusion lymphoma, [4] HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome. [5]
Kaposi sarcoma often occurs in patients with acquired immune deficiency syndrome. Kaposi sarcoma, however, has different characteristics from typical soft-tissue sarcomas and is treated differently. [8] In a very small fraction of cases, sarcoma may be related to a rare inherited genetic alteration of the TP53 gene and is known as Li-Fraumeni ...
Moritz Kaposi (Hungarian: Kaposi Mór, pronounced [ˈkɒpoʃi ˈmoːr]; 23 October 1837 – 6 March 1902) was a physician and dermatologist from the Austro-Hungarian Empire who discovered the skin tumor that received his name (Kaposi's sarcoma).
Starting with a case of shingles in February 1981, [24] Bobbi Campbell suffered a succession of unusual illnesses, including leukopenia later that summer. [24] After hiking the Pinnacles National Monument with his boyfriend in September that year, he noticed on his feet lesions of Kaposi's sarcoma (KS), [17] [24] then thought of as a rare cancer of elderly Jewish men but with alarming numbers ...
Dermatofibrosarcoma protuberans (DFSP) [2] is a rare locally aggressive malignant cutaneous soft-tissue sarcoma. DFSP develops in the connective tissue cells in the middle layer of the skin (dermis). [3] Estimates of the overall occurrence of DFSP in the United States are 0.8 to 4.5 cases per million persons per year.
By 1984, a number of case reports had been published describing a multicentric variant of the disease and with some reports describing an association with Kaposi's sarcoma. [17] In 1995, the association between HHV-8 and Castleman disease was described in patients with HIV . [ 18 ]