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Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. [ 1 ] In neurodegenerative diseases , cells of the central nervous system stop working or die via neurodegeneration .
Degeneration is deterioration in the medical sense.Generally, it is the change from a higher to a lower form. More specifically, it is the change of tissue to a lower or less functionally active form.
Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]
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The most common form of myelopathy in humans, cervical spondylotic myelopathy (CSM), [2] [3] also called degenerative cervical myelopathy, [4] results from narrowing of the spinal canal (spinal stenosis) ultimately causing compression of the spinal cord. [5] When due to trauma, myelopathy is known as (acute) spinal cord injury.
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Thakker–Donnai syndrome; Thalamic degeneration symmetrical infantile; Thalamic degenerescence infantile; Thalamic syndrome; Thalassemia major; Thalassemia minor
Nguyễn Đình Chiểu was born in the southern province of Gia Định, the location of modern Saigon.He was of gentry parentage; his father was a native of Thừa Thiên–Huế, near Huế; but, during his service to the imperial government of Emperor Gia Long, he was posted south to serve under Lê Văn Duyệt, the governor of the south.