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Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults. [3] However, clinical data suggests there is a similar reduction of LDL cholesterol and cardiovascular events at any dose in this population and adults younger than 65 years of age.
Atorvastatin Combining gemfibrozil and a statin increases risk of rhabdomyolysis and subsequently kidney failure [62] [63] Persons taking the anticoagulant warfarin: Any statin The statin use may require that the warfarin dose be changed, as some statins increase the effect of warfarin. [64]
Ultimately, the study found disparate results for all cause mortality with HRT, finding it to be lower when HRT was begun during ages 50–59, but higher when begun after age 60. The authors of the study recommended that women with non-surgical menopause take the lowest feasible dose of hormones for the shortest time to minimize risk. [97]
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Women with vasomotor symptoms during menopause seem to have an especially unfavorable cardiometabolic profile, [36] as well as women with premature onset of menopause (before 45 years of age). [37] These risks can be reduced by managing risk factors, such as tobacco smoking, hypertension , increased blood lipids and body weight.
Women who have had a hysterectomy tend to go through menopause early and have a nearly twofold increased risk of POI. [15] Almost any pelvic surgery has the potential to damage the ovary by affecting its blood supply or causing inflammation in the area resulting in POI, especially surgery to the ovaries themselves (e.g. for treatment of ovarian ...