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Healthcare professionals aren’t sure why some people develop nonalcoholic fatty liver while others develop NASH. If you have fatty liver disease, you’re more likely to develop health ...
All cause mortality in MASH is 25.5 per 1000 person years with a liver specific mortality of 11.7 per 1000 person years. The most common cause of death in those with MASH is cardiovascular disease. [3] MASH is associated with a 1.7 times overall mortality, 15 times liver specific mortality and 12 times risk of liver cancer as compared to MASLD. [3]
The degree of elevation (i.e. levels in the hundreds vs. in the thousands), the predominance for AST vs. ALT elevation, and the ratio between AST and ALT are informative of the diagnosis. [32] Ultrasound, CT, and MRI can all identify steatosis (fatty changes) of the liver tissue and nodularity of the liver surface suggestive of cirrhosis.
Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [ 1 ] [ 2 ] Occasionally there may be tiredness or pain in the upper right side of the abdomen . [ 1 ]
For people with NASH and end-stage liver disease, liver failure, or liver cancer, liver transplantation is an accepted procedure according to the EASL. [16] People with NASH cirrhosis NASH who are being considered for a liver transplant warrant systematic evaluation for cardiovascular diseases (whether the symptoms are apparent or not).
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