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  2. Gastrointestinal intraepithelial neoplasia - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal...

    Cancers of the GI tract (esophageal, gastric, and colorectal) are on the rise. Over the last 30 years there has been an increase in incidence of adenocarcinoma of the esophagus, gastroesophageal junction, and gastric cardia. [3] Gastric cancer is the fourth most common malignant tumor and third most common cause of cancer related death.

  3. Esophageal cancer - Wikipedia

    en.wikipedia.org/wiki/Esophageal_cancer

    In contrast to squamous-cell carcinoma, esophageal adenocarcinoma is more common in white American men (over the age of 60) than it is in African Americans. Multiple reports indicate esophageal adenocarcinoma incidence has increased during the past 20 years, especially in non-Hispanic white men.

  4. Oesophagogastric junctional adenocarcinoma - Wikipedia

    en.wikipedia.org/wiki/Oesophagogastric_junction...

    The diagnostic workup for OGJ adenocarcinoma usually involves performing an endoscopy with endoscopic biopsy of suspicious looking tissue. Accurate staging of tumor extent and involvement of surrounding tissue or distant metastases is critical to establishing a prognosis, and is usually guided by endoscopic ultrasound, computed tomography scans, and/or positron emission tomography scans to ...

  5. Siewert classification - Wikipedia

    en.wikipedia.org/wiki/Siewert_classification

    Adenocarcinoma of the distal part of the esophagus. The tumor center is located 1–5 cm above the gastric cardia. ... Adenocarcinoma of the subcardial stomach. The ...

  6. Gastrointestinal cancer - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_cancer

    Barrett's esophagus is the dominant pre-malignant lesion of esophageal adenocarcinoma, [18] and has prevalent epigenetic alterations. [19] Esophageal squamous-cell carcinomas may occur as second primary tumors associated with head and neck cancer, due to field cancerization (i.e. a regional reaction to long-term carcinogenic exposure).

  7. Barrett's esophagus - Wikipedia

    en.wikipedia.org/wiki/Barrett's_esophagus

    The incidence of esophageal adenocarcinoma has increased substantially in the Western world in recent years. [1] The condition is found in 5–15% of patients who seek medical care for heartburn (gastroesophageal reflux disease, or GERD), although a large subgroup of patients with Barrett's esophagus are asymptomatic.

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