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Catharanthus roseus, commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, [2] is a perennial species of flowering plant in the family Apocynaceae.
Catharanthus is a genus of flowering plants in the family Apocynaceae.Like the genus Vinca, they are known commonly as periwinkles. [3] There are eight known species. Seven are endemic to Madagascar, [4] though one, C. roseus, is widely naturalized around the world.
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
Vinca alkaloids were originally manufactured by extracting them from Catharanthus roseus (Madagascar Periwinkle). [1] Podophyllum spp. Two chemotherapy drugs, etoposide and teniposide, are synthetic chemical compounds similar in chemical structure to the toxin podophyllotoxin which is found in Podophyllum peltatum (May Apple). [1] Taxus brevifolia
The diverse flora of Madagascar holds potential for natural product research and drug production on an industrial scale; the Madagascar periwinkle (Cataranthus roseus), a source of alkaloids used in the treatment of different cancers, is a famous example. [62]
The use of drugs (whether chemotherapy, ... Vinca alkaloids are derived from the Madagascar periwinkle, Catharanthus roseus, [48] [49] formerly known as Vinca rosea ...
Periwinkle, a common name for a number of gastropod molluscs in the family Littorinidae. Common periwinkle (Littorina littorea) ... Catharanthus or Madagascar periwinkles
[111] [45] The Vinca alkaloids vincristine and vinblastine, used as anti-cancer drugs, were discovered in the 1950s from the Madagascar periwinkle, Catharanthus roseus. [112] Hundreds of compounds have been identified using ethnobotany, investigating plants used by indigenous peoples for possible medical applications. [113]