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Adenovirus infection is a contagious viral disease, caused by adenoviruses, commonly resulting in a respiratory tract infection. [ 1 ] [ 9 ] Typical symptoms range from those of a common cold , such as nasal congestion , rhinitis , and cough , to difficulty breathing as in pneumonia . [ 9 ]
Equine adenovirus 1 can also cause fatal disease in immunocompromised Arabian foals, involving pneumonia and destruction of pancreatic and salivary gland tissue. [31] Tupaia adenovirus (TAV) (tree shrew adenovirus 1) has been isolated from tree shrews. Otarine adenovirus 1 has been isolated from sea lions (Zalophus californianus). [32]
In the past nucleic acid tests have mainly been used as a secondary test to confirm positive serological results. [3] However, as they become cheaper and more automated, they are increasingly becoming the primary tool for diagnostics and can also be use for monitoring of treatment of viral infected individuals t.
Human adenovirus 41 (HAdV-F41), is an enteric Adenovirus, a nonenveloped virus with an icosahedral nucleocapsid containing a double-stranded DNA genome. [ 1 ] It can particularly target the gastrointestinal tract to cause gastroenteritis , with symptoms similar to rotavirus gastroenteritis and norovirus . [ 2 ]
The example used for the following description is Human adenovirus E, a mastadenovirus with a 36 Kbp genome containing 38 protein-coding genes. [2] While the precise number and identity of genes varies among adenoviruses, the basic principles of genome organization and the functions of most of the genes described in this article are shared ...
Adenovirus serotype 14 (Ad14) is a serovar of adenovirus which, unlike other adenovirus serovars, is known to cause potentially fatal adenovirus infections.According to the United States Centers for Disease Control and Prevention (CDC), as of September 2007, outbreaks have been identified in four states in the U.S., with ten identified deaths since May 2006.
Viral culture is a laboratory technique [1] in which samples of a virus are placed to different cell lines which the virus being tested for its ability to infect. If the cells show changes, known as cytopathic effects, then the culture is positive.
Contamination has risen within and among laboratories. CPEs can be used to test the purity of a certain cell line. For example, HeLa CCL-2 is a common cell line used in a wide variety of research areas. To test the purity of the HeLa cells, CPEs were observed that occurred after inoculation with Coxsackievirus B3. These CPEs included morphology ...