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Accurate computer models of a treatment and its deployment, as well as patient characteristics, are necessary precursors for the development of in silico clinical trials. [5] [6] [8] [9] In such a scenario, ‘virtual’ patients would be given a ‘virtual’ treatment, enabling observation through a computer simulation of how the candidate biomedical product performs and whether it produces ...
The term in silico was first used in 1989 at a workshop "Cellular Automata: Theory and Applications" by a mathematician from National Autonomous University of Mexico (UNAM). [2] The term in silico radiation oncology, a precursor of generic in silico medicine was coined and first introduced by G. Stamatakos in Proceedings of the IEEE in 2002. [3]
TTD includes information about successful, clinical trial and research targets, approved, clinical trial and experimental drugs linked to their primary targets, new ways to access data by drug mode of action, recursive search of related targets or drugs, similarity target and drug searching, customized and whole data download, and standardized ...
[1] [2] The expression in silico was first used to characterize biological experiments carried out entirely in a computer in 1989, in the workshop "Cellular Automata: Theory and Applications" in Los Alamos, New Mexico, by Pedro Miramontes, a mathematician from National Autonomous University of Mexico (UNAM), presenting the report "DNA and RNA ...
Cheminformatics (also known as chemoinformatics) refers to the use of physical chemistry theory with computer and information science techniques—so called "in silico" techniques—in application to a range of descriptive and prescriptive problems in the field of chemistry, including in its applications to biology and related molecular fields.
Insilico Medicine is a biotechnology company headquartered in Boston, Massachusetts, [2] with additional facilities in Pak Shek Kok, Hong Kong in Hong Kong Science Park near the Chinese University of Hong Kong, [3] and in New York, at The Cure by Deerfield. The company combines genomics, big data analysis, and deep learning for in silico drug ...
Naunyn-Schmiedeberg's Archives of Pharmacology (formerly Naunyn-Schmiedebergs Archiv für Pharmakologie and Naunyn-Schmiedebergs Archiv für Pharmakologie und experimentelle Pathologie) is a peer-reviewed scientific journal of pharmacology. The journal was established in 1873 by Bernhard Naunyn, Oswald Schmiedeberg, and Edwin Klebs.
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy is a monthly peer-reviewed medical journal covering human pharmacology and pharmacotherapy, published by Wiley-Blackwell on behalf of the American College of Clinical Pharmacy, of which it is an official journal.