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Chlorhexidine [1] is a disinfectant and antiseptic with the molecular formula C 22 H 30 Cl 2 N 10, which is used for skin disinfection before surgery and to disinfect surgical instruments. [2] It is also used for cleaning wounds , preventing dental plaque , treating yeast infections of the mouth , and to keep urinary catheters from blocking. [ 3 ]
Comparison between octenidine and chlorhexidine determined by the suspension test after 5 minutes of exposure. Effective concentration, % Octenidine dihydrochloride Chlorhexidine digluconate Staphylococcus aureus: 0.025 >0.2 Escherichia coli: 0.025 0.1 Proteus mirabilis: 0.025 >0.2 Candida albicans: 0.01 0.025 Pseudomonas aeruginosa: 0.025 >0.2
Skin disinfection may be accomplished with a number of solutions including providone-iodine, chlorhexidine, alcohol based solutions, and cetrimide. [2] There is strong evidence that chlorhexidine and denatured alcohol use to clean skin prior to surgery is better than any other commercially available antiseptic, such as povidone-iodine with alcohol.
Hexetidine is not the same as Chlorhexidine, another chemical commonly used in mouthwash, or the antimicrobial drug Hexedene (C 22 H 45 N 3). [2] In the UK, hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. In Canada, hexetidine was the active ingredient in the medicated mouthwash branded Steri/sol which has been ...
Diguanides including chlorhexidine gluconate, a bacteriocidal antiseptic which (with an alcoholic solvent) is considered a safe and effective antiseptic for reducing the risk of infection after clean surgery, [11] including tourniquet-controlled upper limb surgery. [12] It is also used in mouthwashes to treat inflammation of the gums .
Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.In dermatological use, [4] it is spelled polihexanide and sold under various brand names. [5]