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  2. Gemfibrozil - Wikipedia

    en.wikipedia.org/wiki/Gemfibrozil

    It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids in fat cells. [3] Gemfibrozil was patented in 1968, and came into medical use in 1982. [6] It is available as a generic medication. [4] In 2022, it was the 231st most commonly prescribed medication in the United States, with more than 1 million ...

  3. Cardiovascular agents - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_agents

    Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    As of 2018, the best available evidence favors low-dose thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. [5] Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of ...

  5. Lipid-lowering agent - Wikipedia

    en.wikipedia.org/wiki/Lipid-lowering_agent

    Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...

  6. Management of hypertension - Wikipedia

    en.wikipedia.org/wiki/Management_of_hypertension

    For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]

  7. C15H22O3 - Wikipedia

    en.wikipedia.org/wiki/C15H22O3

    Gemfibrozil, an oral drug used to lower lipid levels; Nardosinone, a sesquiterpene; Octyl salicylate, an ingredient in sunscreens; Sterpuric acid, a sesquiterpene;

  8. Fibrate - Wikipedia

    en.wikipedia.org/wiki/Fibrate

    Fewer large-scale trials have been conducted with fibrates than with statins and the results are less conclusive, but reduced rates of cardiovascular disease have been reported with fibrate therapy in the subgroup of patients with low HDL-C levels and elevated TG (e.g. TG > 2.3 mmol/L (200 mg/dL)).

  9. Dyslipidemia - Wikipedia

    en.wikipedia.org/wiki/Dyslipidemia

    [20] [21] They include fenofibrate, gemfibrozil, and bezafibrate and work to decrease triglycerides, increase HDL-C, and also decrease LDL-C which is variable depending on which drug is used. The FIELD Study showed that fenofibrate reduced both coronary revascularization as well as nonfatal myocardial infarctions (but not in patients with type ...

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