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Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...
Runners can experience a euphoric state often called a "runner's high". The runner's high is a transient state of euphoria coupled with lessened feelings of anxiety and a higher pain threshold, which can come either from continuous moderate physical exertion over time or from short bursts of high-intensity exercise.
This normal function is called aerobic metabolism and does not produce lactic acid if enough oxygen is present. During heavy exercise such as long distance running or any demanding exercise, the body's need for oxygen to produce energy is higher than the oxygen supplied in the blood from respiration.
Endorphins may contribute to the positive effect of exercise on anxiety and depression. [43] The same phenomenon may also play a role in exercise addiction . Regular intense exercise may cause the brain to downregulate the production of endorphins in periods of rest to maintain homeostasis , causing a person to exercise more intensely in order ...
Running and other high-intensity exercises have also been shown to suppress appetite by releasing a chemical compound known as Lac-Phe - a combination of lactate and phenylalanine. This can help ...
One such region is the nucleus accumbens—a key part of the brain’s reward system that’s fueled by dopamine, a chemical that Wise fondly refers to as “the slutty neurotransmitter” because ...
Macrophages of the reticuloendothelial system store iron as part of the process of breaking down and processing hemoglobin from engulfed red blood cells. Iron is also stored as a pigment called hemosiderin, which is an ill-defined deposit of protein and iron, created by macrophages where excess iron is present, either locally or systemically, e ...
An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood ... “Tens of millions of people in the U.S. are basically running on fumes either because there ...