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Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. The instruments are usually a hypodermic needle and a syringe.
For some injections, especially deeper injections, a local anesthetic is given. [30] When giving an injection to young children or infants, they may be distracted by giving them a small amount of sweet liquid, such as sugar solution, [ 31 ] or be comforted by breastfeeding [ 32 ] during the injection, which reduces crying.
A narrow, high-pressure stream of liquid is made to penetrate the outermost layer of the skin (stratum corneum) to deliver medication to targeted underlying tissues of the epidermis or dermis ("cutaneous" injection, also known as classical "intradermal" injection), fat ("subcutaneous" injection), or muscle ("intramuscular" injection).
Subcutaneous: Subcutaneous injections are given at a 45-degree angle, usually in the thigh (for babies under the age of 12 months) or upper-outer triceps area for people over 12 months. The MMR ...
Injection into the subcutaneous tissue is a route of administration used for drugs such as insulin: because it possesses few blood vessels, the tissue absorbs drugs slowly. [10]: 135 Subcutaneous injection is believed to be the most effective manner to administer some drugs, such as human growth hormones. Just as the subcutaneous tissue can ...
The dosage given is usually less than 0.5 mL, less than given subcutaneously or intramuscularly. A 1 ⁄ 4 -to- 1 ⁄ 2 -inch-long (6 to 13 mm) and 26 or 27 gauge thick hypodermic needle is used. [ 1 ]
Subcutaneous (under the skin). [22] This generally takes the form of subcutaneous injection, e.g. with insulin. Skin popping is a slang term that includes subcutaneous injection, and is usually used in association with recreational drugs. In addition to injection, it is also possible to slowly infuse fluids subcutaneously in the form of ...
On Monday, Larimar Therapeutics, Inc. (NASDAQ:LRMR) released initial data from the ongoing long-term OLE study evaluating daily subcutaneous injections of 25 mg of nomlabofusp self-administered or ...