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Malignancy; Other names: Cancer, malignant neoplasm: Malignant tumor (right) spreads uncontrollably and invades the surrounding tissues; benign tumor (left) remains self-contained from neighbouring tissue: Specialty: Oncology: Symptoms: Fatigue, lump(s), change in skin, abnormal bleeding, prolonged cough, unexplained weight loss [1] Risk factors
World-wide, liver cancer mortality is more often due to hepatitis B virus (HBV) (33%), less often due to hepatitis C virus (HCV) (21%), and still frequently due to alcohol use (30%). [34] World-wide, liver cancer is the 4th most frequent cause of cancer mortality, causing 9% of all cancer mortality (total liver cancer deaths in 2015 being ...
Most cancer deaths are due to cancer that has metastasized. [39] Metastasis is common in the late stages of cancer and it can occur via the blood or the lymphatic system or both. The typical steps in metastasis are: Local invasion; Intravasation into the blood or lymph. Circulation through the body. Extravasation into the new tissue. Proliferation
Cancer related to one's occupation is believed to represent between 2–20% of all cases. [17] Most cancer deaths caused by occupational risk factors occur in the developed world. [16] Job stress does not appear to be a significant factor at least in lung, colorectal, breast and prostate cancers. [18]
In the U.S. cancer is second only to cardiovascular disease as the leading cause of death; [20] in the UK it is the leading cause of death. [21] In many developing countries cancer incidence , insofar as this can be measured, appears much lower, most likely because of the higher death rates due to infectious disease or injury.
Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists).
This represents about 3% of the almost seven million deaths due to cancer that year, and about 0.35% of all deaths from any cause. [79] Of the sixteen separate sites the body compared, leukemia was the 12th most common class of neoplastic disease and the 11th most common cause of cancer-related death. [79]
Tumor markers may be used for the following purposes: Monitoring the malignancy; When a malignant tumor is found by the presence of a tumor marker, the level of marker found in the body can be monitored to determine the state of the tumor and how it responds to treatment.