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Borrelia burgdorferi is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans. [ 1 ] [ 2 ] Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato .
Borrelia is a genus of bacteria of the spirochete phylum. [1] Several species cause Lyme disease , also called Lyme borreliosis, a zoonotic , vector-borne disease transmitted by ticks . Other species of Borrelia cause relapsing fever , and are transmitted by ticks or lice , depending on the species of bacteria. [ 2 ]
Lyme disease, also known as Lyme borreliosis, is a tick-borne disease caused by species of Borrelia bacteria, transmitted by blood-feeding ticks in the genus Ixodes. [4] [9] [10] The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. [1]
[3] [4] Borrelia species in the species complex known to cause Lyme disease are collectively called Borrelia burgdorferi sensu lato (s.l.), not to be confused with the single species Borrelia burgdorferi sensu stricto, a member of the complex, which is responsible for nearly all cases of Lyme disease in North America. [5]
Neuroborreliosis is often preceded by the typical symptoms of Lyme disease, which include erythema migrans and flu-like symptoms such as fever and muscle aches. Neurologic symptoms of neuroborreliosis include the meningoradiculitis (which is more common in European patients), cranial nerve abnormalities, and altered mental status.
The initial sign of about 80% of Lyme infections is an erythema migrans (EM) rash at the site of a tick bite, often near skin folds, such as the armpit, groin, or back of knee, on the trunk, under clothing straps, or in children's hair, ear, or neck.
Several studies have failed to detect Borrelia burgdorferi, which is the causative agent of Lyme disease, in patients from the southern United States. [ 5 ] [ 6 ] This disease may be caused by the related bacterium Borrelia lonestari , [ 7 ] [ 8 ] which is a spirochete first isolated in culture in 2004. [ 9 ]
Main article: Human parasite Endoparasites Protozoan organisms Common name of organism or disease Latin name (sorted) Body parts affected Diagnostic specimen Prevalence Source/Transmission (Reservoir/Vector) Granulomatous amoebic encephalitis and Acanthamoeba keratitis (eye infection) Acanthamoeba spp. eye, brain, skin culture worldwide contact lenses cleaned with contaminated tap water ...