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  2. Aflibercept - Wikipedia

    en.wikipedia.org/wiki/Aflibercept

    Aflibercept, sold under the brand names Eylea and Zaltrap among others, is a medication used to treat wet macular degeneration and metastatic colorectal cancer. [ 16 ] [ 17 ] It was developed by Regeneron Pharmaceuticals .

  3. Faricimab - Wikipedia

    en.wikipedia.org/wiki/Faricimab

    Faricimab is a 150kDa-sized bispecific antibody whose molecular structure allows a high affinity bond to both vascular endothelial growth factor A (VEGF-A) and Angiopoietin (Ang-2). [9] By blocking the action of these two growth factors, faricimab decreases migration and replication of endothelial cells allowing for stabilization of vascular ...

  4. Basis of estimate - Wikipedia

    en.wikipedia.org/wiki/Basis_of_estimate

    A pivot table in BOEMax, a Basis of Estimate software package. To create a BOE companies, throughout the past few decades, have used spreadsheet programs and skilled cost analysts to enter thousands of lines of data and create complex algorithms to calculate the costs. These positions require a high level of skill to ensure accuracy and ...

  5. European regulator endorses high-dose version of Bayer eye ...

    www.aol.com/news/european-regulator-endorses...

    A go-ahead would mean that Eylea, an injection in the eye also known as aflibercept and jointly developed with Regeneron, European regulator endorses high-dose version of Bayer eye drug Eylea Skip ...

  6. Cost basis - Wikipedia

    en.wikipedia.org/wiki/Cost_basis

    Basis (or cost basis), as used in United States tax law, is the original cost of property, adjusted for factors such as depreciation. When a property is sold, the taxpayer pays/(saves) taxes on a capital gain /(loss) that equals the amount realized on the sale minus the sold property's basis.

  7. US FDA approves two biosimilars for blockbuster eye drug Eylea

    www.aol.com/news/us-fda-approves-two-biosimilars...

    The agency approved Biocon Biologics' Yesafili as well as Samsung Bioepis and Biogen's Opuviz, while also allowing interchangeability, or the drug's substitution with biosimilars without the need ...

  8. Chemical plant cost indexes - Wikipedia

    en.wikipedia.org/wiki/Chemical_plant_cost_indexes

    Chemical plant cost indexes are dimensionless numbers employed to updating capital cost required to erect a chemical plant from a past date to a later time, following changes in the value of money due to inflation and deflation. Since, at any given time, the number of chemical plants is insufficient to use in a preliminary or predesign estimate ...

  9. Adjusted basis - Wikipedia

    en.wikipedia.org/wiki/Adjusted_basis

    In tax accounting, adjusted basis is the net cost of an asset after adjusting for various tax-related items. [1] Adjusted Basis or Adjusted Tax Basis refers to the original cost or other basis of property, reduced by depreciation deductions and increased by capital expenditures. Example: Muhammad buys a lot for $100,000. He then erects a retail ...

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