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Risk factors include exposure to ionizing radiation such as during radiation therapy, a family history of the condition, and neurofibromatosis type 2. [2] [3] They appear to be able to form from a number of different types of cells including arachnoid cells. [1] [2] Diagnosis is typically by medical imaging. [2]
Meningiomas are significantly more common in women than in men; they are most common in middle-aged women. Two predisposing factors associated with meningiomas for which at least some evidence exists are exposure to ionizing radiation (cancer treatment of brain tumors) and hormone replacement therapy.
Meningiomas have an incidence of ~4.18/100,000 persons each year. Thus, ~10,000 meningiomas are diagnosed in the US each year; corresponding to ~100 cases of ONSM each year in the US. The actual number of meningiomas is likely much higher as it is very common in elderly women [citation needed]. ONSM comprises about 2% of orbital tumors, and ...
Meningiomas have been divided into three types based on their patterns of growth. Histological factors that increase the grade include a high number of mitotic figures, necrosis and local invasion. Treatment of sphenoid wing meningiomas often depends on the location and size of the tumor. Gamma knife radiation and microscopic surgery are common ...
The causes of CNS tumors are poorly understood. A few risk factors are known, including radiation exposure, genetic disorder, a family history of CNS tumors, immunodeficiency, stress and a history of previous cancers. As with all cancers, the risk of developing a CNS tumor increases with age. [10]
Neurofibromatosis type II (also known as MISME syndrome – multiple inherited schwannomas, meningiomas, and ependymomas) is a genetic condition that may be inherited or may arise spontaneously, and causes benign tumors of the brain, spinal cord, and peripheral nerves.
There are many genetic factors associated with intradural tumors, most commonly neurofibromatosis 1 (NF1), neurofibromatosis 2 (NF2), and Von-Hippel Lindau (VHL) syndrome. [1] The most common type of intradural-extramedullary tumors are meningiomas and nerve-sheath tumors. [5]
Cutaneous meningioma, also known as heterotopic meningeal tissue, and rudimentary meningocele [1] is a developmental defect, and results from the presence of meningocytes outside the calvarium. [ 2 ] : 622
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