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The sleep cycle is an oscillation between the slow-wave and REM (paradoxical) phases of sleep. It is sometimes called the ultradian sleep cycle, sleep–dream cycle, or REM-NREM cycle, to distinguish it from the circadian alternation between sleep and wakefulness. In humans, this cycle takes 70 to 110 minutes (90 ± 20 minutes). [1]
The sleep cycle of alternate NREM and REM sleep takes an average of 90 minutes, occurring 4–6 times in a good night's sleep. [17] [22] The American Academy of Sleep Medicine (AASM) divides NREM into three stages: N1, N2, and N3, the last of which is also called delta sleep or slow-wave sleep. [23]
The basic rest–activity cycle (BRAC) is a physiological arousal mechanism in humans proposed by Nathaniel Kleitman, [1] hypothesized to occur during both sleep and wakefulness. Empirically, it is an ultradian rhythm of approximately 90 minutes (80–120 minutes [ 2 ] ) characterized by different levels of excitement and rest.
Known as slow-wave sleep or stage 3 non-REM sleep, this is the deepest stage of sleep and the hardest to wake up from. Brain activity slows down, muscles and bones strengthen, hormones regulate ...
REM sleep typically occupies 20–25% of total sleep in adult humans: about 90–120 minutes of a night's sleep. The first REM episode occurs about 70 minutes after falling asleep. Cycles of about 90 minutes each follow, with each cycle including a larger proportion of REM sleep. [27]
Slow-wave sleep (SWS), often referred to as deep sleep, is the third stage of non-rapid eye movement sleep (NREM), where electroencephalography activity is characterised by slow delta waves. [ 2 ] Slow-wave sleep usually lasts between 70 and 90 minutes, taking place during the first hours of the night. [ 3 ]