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Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
Cyanocobalamin is the most common form used in dietary supplements and food fortification because cyanide stabilizes the molecule against degradation. Methylcobalamin is also offered as a dietary supplement. [12] There is no advantage to the use of adenosylcobalamin or methylcobalamin forms for the treatment of vitamin B 12 deficiency. [20] [21 ...
Medications: long-term use of certain medications can result in poor absorption of dietary vitamin B 12. [1] These include medications to treat heartburn, and metformin to treat diabetes. [132] [133] A genetic disorder, transcobalamin II deficiency, or Imerslund–Gräsbeck syndrome can be a cause. Nitrous oxide exposure, and recreational use ...
Commonly cyanocobalamin or methylcobalamin in vitamin supplements. A coenzyme involved in the metabolism of all animal cells, especially affecting DNA synthesis and regulation, but also fatty acid metabolism and amino acid metabolism .
Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. [1] [2] Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
cyanocobalamin, hydroxocobalamin, methylcobalamin, adenosylcobalamin: water 2.4 μg/2.4 μg vitamin B 12 deficiency anemia [18] none proven meat, poultry, fish, eggs, milk C: ascorbic acid: water 90 mg/75 mg scurvy: stomach pain, diarrhoea, and flatulence. [19] many fruits and vegetables, liver D D 1