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Clasp-knife response refers to a Golgi tendon reflex with a rapid decrease in resistance when attempting to flex a joint, usually during a neurological examination. It is one of the characteristic responses of an upper motor neuron lesion .
This causes increased resistance to passive movement (that the patient does not initiate), called spasticity, which is associated with another neurological sign, the clasp-knife response, in which the spastic muscle initially resists passive movement strongly, and then suddenly yields—like the motion of a pocketknife.
A commonly known feature of spasticity, known as Clasp-knife response is the sudden decrease of tone after initial resistance, also referred to as a lengthening reaction or a "catch-yield sequence". [9]
Clasp-knife response where initial higher resistance to movement is followed by a lesser resistance; Babinski sign is present, where the big toe is raised (extended) rather than curled downwards (flexed) upon appropriate stimulation of the sole of the foot. The presence of the Babinski sign is an abnormal response in adulthood.
Spasticity can be in the form of the clasp-knife response, in which there is increased resistance only at the beginning or at the end of the movement. Rigidity can be of the leadpipe type, in which there is resistance throughout to passive movement, or it may be of cogwheel type, in which the resistance to passive movement is in a jerky manner.
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Symptoms associated with central nervous systems disorders are classified into positive and negative categories. Positive symptoms include those that increase muscle activity through hyper-excitability of the stretch reflex (i.e., rigidity and spasticity) where negative symptoms include those of insufficient muscle activity (i.e. weakness) and reduced motor function. [5]
A lower motor neuron lesion is a lesion which affects nerve fibers traveling from the lower motor neuron(s) in the anterior horn/anterior grey column of the spinal cord, or in the motor nuclei of the cranial nerves, to the relevant muscle(s).