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Why trust Cosmopolitan?. Beth Gillette is the beauty editor at Cosmopolitan with six years of experience researching, writing, and editing skincare stories that range from a robust Olay Super ...
Tretinoin (retinoic acid)causes dispersion of pigment granules in keratinocytes,interferes with pigment transfer,and acceler-ates epidermal transfer,thus causing pigment to be lost more rapidly.Tretinoin also accelerates epidermal turnover,shorten-ing the "transit time"from the basal layer and accelerating pig-ment loss.Retinoic acid reduces ...
Tretinoin was patented in 1957 and approved for medical use in 1962. [13] It is on the World Health Organization's List of Essential Medicines. [14] Tretinoin is available as a generic medication. [15] In 2022, it was the 238th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [16] [17]
Effective agents for specific areas include corticosteroids, tretinoin, and hydroquinone. [6] These agents are not allowed in cosmetics in Europe due to concerns about side effects. [6] Attempts to whiten large areas of skin may also be carried out by certain cultures. [6] This may be done for reasons of appearance, politics, or economics. [6]
Although this approach diluted the bad news for Janssen, there were still two problems. First, the gynecomastia rates remained high. Second, one table showed a statistically significant relationship between elevated prolactin and breasts among boys who had been taking the drug for eight weeks. In other words, it looked like causation had been ...
Brandon had been asked by one of the lawyers working the cases to go back through all of the clinical studies J&J had turned over, each of which typically contained dozens of pages of text and tables attached to hundreds of pages of data. She was told to separate out the studies involving children and summarize them. It was a weeks-long project.
On the Flip Side: 100-Year-Old Companies Still in Business Today And instead of shopping at specialty stores, Target, Walmart and Amazon have become the go-to for buying just about everything.
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