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Ankylosing spondylitis is a member of the more broadly defined disease axial spondyloarthritis. [ 23 ] [ 24 ] Axial spondyloarthritis can be divided into two categories: radiographic axial spondyloarthritis (which is a synonym for ankylosing spondylitis) and non-radiographic axial spondyloarthritis (which include less severe forms and early ...
The prevalence of ankylosing spondylitis and spondyloarthritis, in particular, varies across populations and is similar to that of HLA-B27. [5] The incidence of spondyloarthritis as a disease entity was recorded in only four investigations, and ranged from 0.48/100,000 in Japan [ 54 ] to 62.5/100,000 in Spain .
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
SMA is a category of spinal disease that in linked with genetic disorders. More specifically, it is caused by an autosomal recessive disorder due to a homozygous mutation of a motor neuron gene. [3]
Knee osteoarthritis has the highest prevalence from all types of osteoarthritis, with 33.1% in rural South Africa; Ankylosing spondylitis: 0.1% in South Africa (rural setting) Psoriatic arthritis: 4.4% in South Africa (urban setting) Gout: 0.7% in South Africa (urban setting) Juvenile idiopathic arthritis: 0.3% in Egypt (urban setting)
Chronic arthritis or sacroiliitis occurs in 15–30 percent of cases. Repeated attacks over many years are common, and patients sometimes end up with chronic and disabling arthritis, heart disease, amyloid deposits, ankylosing spondylitis, immunoglobulin A nephropathy, cardiac conduction abnormalities, or aortitis with aortic regurgitation. [20]
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