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The corneal epithelium (epithelium corneae anterior layer) is made up of epithelial tissue and covers the front of the cornea. It acts as a barrier to protect the cornea, resisting the free flow of fluids from the tears, and prevents bacteria from entering the epithelium and corneal stroma.
The fibrils of each lamella are parallel with one another, but at different angles to those of adjacent lamellae. The lamellae are produced by keratocytes (corneal connective tissue cells), which occupy about 10% of the substantia propria. Apart from the cells, the major non-aqueous constituents of the stroma are collagen fibrils and proteoglycans.
Surface ectoderm forms the lens, corneal epithelium and eyelid. The extracellular mesenchyme forms the sclera, the corneal endothelium and stroma, blood vessels, muscles, and vitreous. The eye begins to develop as a pair of optic vesicles on each side of the forebrain at the end of the fourth week of pregnancy.
The limbal ring is a visible dark ring around the iris of the eye composed of darkened areas of the corneal limbus. The outermost epithelial cells are regularly shed and must be replenished through cell proliferation. The cornea is composed of three primary cell types: epithelial cells, corneal fibroblasts, and endothelial cells. [1]
The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. The term "corneosclera" is also used to describe the sclera and cornea together. [1]
Contact lenses cause corneal neovascularization because they restrict oxygen diffusion to the corneal epithelium. In the short term, the cornea responds to oxygen deprivation by increasing blood flow to the corneal limbus, the narrow circular border between the cornea and sclera. Over time, this chronic limbal hyperemia can progress to corneal ...
The middle (third in number; provided the first layer being the anterior and outermost and the sixth layer being the posterior and the inner most), thickest layer is also called the stroma. The sclera, like the cornea, contains a basal endothelium, above which there is the lamina fusca, containing a high count of pigment cells. [6]
The episclera is the outermost layer of the sclera (the white of the eye). [1] It is composed of loose, fibrous, elastic tissue and attaches to Tenon's capsule. [1]A vascular plexus is found between the bulbar conjunctiva and the sclera consisting of two layers of vessels, the superficial episcleral vessels and the deep episcleral vessels.