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Abnormal blood tests are frequent, accounting for over 50% of cases, but are not diagnostic. [28] [31] Lymphopenia is the most common blood anomaly in sarcoidosis. [28] Anemia occurs in about 20% of people with sarcoidosis. [28] Leukopenia is less common and occurs in even fewer cases but is rarely severe. [28]
Scar sarcoid (also known as "Sarcoidosis in scars") is a cutaneous condition characterized by infiltration and elevation of tattoos and old flat scars due to sarcoidosis. [2]: 710 Mucosal sarcoidosis is a cutaneous condition characterized by pinhead-sized papules that may be grouped and fused together to form a flat plaque. [2]: 711
Incidence is highest for individuals younger than 40 and peaks in the age-group from 20 to 29 years; a second peak is observed for women over 50. [8] [9] Sarcoidosis occurs throughout the world in all races with an average incidence of 16.5/100,000 in men and 19/100,000 in women.
There have been 150,000 to 200,000 diagnosed cases of sarcoidosis in the U.S., and advocates are working to raise awareness and help find a cure.
Löfgren syndrome is a type of acute sarcoidosis, [1] an inflammatory disorder characterized by swollen lymph nodes in the chest, tender red nodules on the shins, fever and arthritis. [2] It is more common in women than men, and is more frequent in those of Scandinavian , Irish , African and Puerto Rican heritage.
Castleman disease (CD) describes a group of rare lymphoproliferative disorders that involve enlarged lymph nodes, and a broad range of inflammatory symptoms and laboratory abnormalities. Whether Castleman disease should be considered an autoimmune disease, cancer, or infectious disease is currently unknown.
It was co-founded by D. Geraint James, who had set up the first international conference on sarcoidosis almost 30 years earlier at the Brompton Hospital. [ 1 ] [ 2 ] [ 3 ] References
The Kveim test, Nickerson-Kveim or Kveim-Siltzbach test is a skin test used to detect sarcoidosis, where part of a spleen from a patient with known sarcoidosis is injected into the skin of a patient suspected to have the disease.