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  2. GMP synthase - Wikipedia

    en.wikipedia.org/wiki/GMP_synthase

    Guanosine monophosphate synthetase, (EC 6.3.5.2) also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. [6]In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides.

  3. Cyclic guanosine monophosphate - Wikipedia

    en.wikipedia.org/wiki/Cyclic_guanosine_monophosphate

    Cyclic guanosine monophosphate (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP). cGMP acts as a second messenger much like cyclic AMP.Its most likely mechanism of action is activation of intracellular protein kinases in response to the binding of membrane-impermeable peptide hormones to the external cell surface. [1]

  4. GMP reductase - Wikipedia

    en.wikipedia.org/wiki/GMP_reductase

    GMP reductase EC 1.7.1.7 (Guanosine 5'-monophosphate oxidoreductase) is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP into IMP. [1] NADPH + guanosine 5-phosphate = NADP + + inosine 5-phosphate + NH 3

  5. Guanosine monophosphate - Wikipedia

    en.wikipedia.org/wiki/Guanosine_monophosphate

    Guanosine monophosphate (GMP), also known as 5′-guanidylic acid or guanylic acid (conjugate base guanylate), is a nucleotide that is used as a monomer in RNA.It is an ester of phosphoric acid with the nucleoside guanosine.

  6. Cyclic guanosine monophosphate–adenosine monophosphate

    en.wikipedia.org/wiki/Cyclic_guanosine...

    Cyclic guanosine monophosphate–adenosine monophosphate (cyclic GMP-AMP, cGAMP) is the first cyclic di-nucleotide found in metazoa. [1] In mammalian cells, cGAMP is synthesized by cyclic GMP-AMP synthase from ATP and GTP upon cytosolic DNA stimulation.

  7. List of enzymes - Wikipedia

    en.wikipedia.org/wiki/List_of_enzymes

    Function: Amylase is an enzyme that is responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates to be turned into simple sugars that will be easier to absorb. Clinical Significance: Amylase also has medical history in the use of Pancreatic Enzyme Replacement Therapy (PERT). One of the components is ...

  8. Cyclic GMP-AMP synthase - Wikipedia

    en.wikipedia.org/wiki/Cyclic_GMP-AMP_synthase

    cGAS dimer, human cGAS-cGAMP-STING pathway. Cyclic GMP-AMP synthase (cGAS, cGAMP synthase), belonging to the nucleotidyltransferase family, is a cytosolic DNA sensor that activates a type-I interferon response.

  9. Guanylyltransferase - Wikipedia

    en.wikipedia.org/wiki/Guanylyltransferase

    Many eukaryotic guanylyl transferases are capping enzymes that catalyze the formation of the 5' cap in the co-transcriptional modification of messenger RNA. Because the 5' end of the RNA molecule ends in a phosphate group, the bond formed between the RNA and the GTP molecule is an unusual 5'-5' triphosphate linkage, instead of the 3' -5 ...