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Its use is advised against in people being concomitantly treated with: [13] [3] [5] [6] [21] [22] ACE inhibitors like captopril , enalapril , lisinopril , perindopril , and ramipril due to the potential for additive hyperkalaemic effects [ 5 ]
One study has shown the allergic reaction rate to be about 3.0% over 359 courses of therapy. [11] Of the allergic reactions, skin rashes, eosinophilia and drug fever were the most common, while serious reactions were less common. Sulfamethoxazole is contraindicated in people with a known hypersensitivity to trimethoprim or sulfonamides. [9]
Brucellosis [4] is a zoonosis caused by ingestion of unpasteurized milk from infected animals, or close contact with their secretions. [5] It is also known as undulant fever, Malta fever, and Mediterranean fever. [6] The bacteria causing this disease, Brucella, are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (coccobacilli ...
Brucella can also target the male reproductive tract. [7] Globally, an estimated 500,000 cases of brucellosis occur each year. [7] Malta fever was a major health problem to British troops in Malta in the 19th and early 20th centuries, resulting in over 6000 cases and 574 deaths. [9]
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, [1] as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.
Brucella melitensis is a Gram-negative coccobacillus bacterium from the Brucellaceae family. The bacterium causes ovine brucellosis , along with Brucella ovis . Humans can become infected if they have contact with an infected animal or its byproducts.