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Veterinarians administer buprenorphine for perioperative pain, particularly in cats, where its effects are similar to morphine. The drug's legal status and lower potential for human abuse makes it an attractive alternative to other opioids. [124] It has veterinary medical use for treatment of pain in dogs and cats, as well as other animals.
The treatment of withdrawal in people with opioid use disorder also relies on symptomatic management and tapering with medications that replace typical opioids, including buprenorphine and methadone. The principle of managing the syndrome is to allow the concentration of drugs in blood to fall to near zero and reverse physiological adaptation.
Buprenorphine was approved by the United States Food and Drug Administration (FDA) in 2002. [8] The lowest optimal dose of buprenorphine is 8 mg. [8] Buprenorphine has fewer withdrawal symptoms upon discontinuation, lower risk for overdose, and lower potential for abuse; therefore, it is more effective for unsupervised treatment than methadone. [8]
Lastly, pain medication such as buprenorphine or meloxicam may be prescribed to reduce swelling and pain during an acute flare-up of cystitis and can assist recovery and provide relief to the cat. This should usually be taken for 7–14 days or until symptoms subside.
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
Liquid medication delivered by syringe is often difficult to induce cats to swallow. The best way to accomplish this is to immobilize the cats head then slip two fingers at the far sides of its mouth.