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2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate . The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips.
An incision wound closed with Dermabond, a cyanoacrylate-based medical adhesive. Cyanoacrylate glue is widely used in human and veterinary medicine. [6] It was in veterinary use for mending bone, hide, and tortoise shell by the early 1970s or before.
There are three cyanoacrylate compounds currently available as topical skin adhesives. 2-Octyl cyanoacrylate is marketed as Dermabond, SurgiSeal, and more recently LiquiBand Exceed. n-Butyl cyanoacrylate is marketed as Histoacryl, Indermil, GluStitch, GluSeal, PeriAcryl, and LiquiBand. The compound ethyl 2-cyanoacrylate is available as Epiglu. [3]
A dermal adhesive (or skin glue) is a glue used to close wounds in the skin as an alternative to sutures, staples, or clips. Glued closure results in less scarring and is less prone to infection than sutured or stapled closure. There is also no residual closure to remove, so follow-up visits for removal are not required.
The medical applications of butyl cyanoacrylate include its use as an adhesive for lacerations of the skin, [5] and in the treatment of bleeding from vascular structures. Butyl cyanoacrylate has been used to treat arteriovenous malformations [ 6 ] by application of the glue into the abnormality through angiography .
Liquid bandages are suitable for clean cuts that close easily and shallow small wounds, as it will help both sides of the wound to bond and produce a suture-like effect.. Due to the drying of liquid wound dressing, it will form a nonelastic film on the wound and cannot absorb tissue flu
Albumin glues (blood glues and egg albumin adhesive, EAA) blood (serum albumin) or eggs: prehistoric Gelatin glues hide glue, including rabbit-skin glue; bone glue, and fish glue including isinglass. Animal connective tissue. and bones hides are acid-treated, neutralized, and repeatedly soaked; the soaking-water is dried into chips hydrolyzed ...
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