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  2. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

  3. Zaleplon - Wikipedia

    en.wikipedia.org/wiki/Zaleplon

    Zaleplon is a high-selectivity, [26] high-affinity ligand of positive modulatory benzodiazepine sites on GABA A receptors. Zaleplon binds preferentially at benzodiazepine sites on α1-containing GABA A receptors (previously known as BZ1/Ω1 receptors), which largely mediate the sedative effects of benzodiazepines. [27]

  4. Insomnia affects up to 50% of adults and can hurt your body ...

    www.aol.com/finance/insomnia-affects-50-adults...

    Insomnia is one of the most common sleep disorders, with the Centers for Disease Control and Prevention reporting that as many as one in two adults experience short-term bouts, while one in 10 may ...

  5. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness . [ 92 ]

  6. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    [113] [114] Long-term use of benzodiazepines in the elderly can lead to a pharmacological syndrome with symptoms including drowsiness, ataxia, fatigue, confusion, weakness, dizziness, vertigo, syncope, reversible dementia, depression, impairment of intellect, psychomotor and sexual dysfunction, agitation, auditory and visual hallucinations ...

  7. Is This the Reason You Can't Sleep? New Study Reveals ... - AOL

    www.aol.com/lifestyle/reason-cant-sleep-study...

    A new study reveals a shocking potential cause for insomnia.

  8. Eszopiclone - Wikipedia

    en.wikipedia.org/wiki/Eszopiclone

    The review made this determination both because of the relatively large dangers to elderly individuals from zolpidem and other "z-drugs" together with the fact the drugs have "minimal efficacy in treating insomnia." This was a change from the 2012 AGS recommendation, which suggested limiting use to 90 days or less.

  9. Neurologists reveal 15 subtle migraine symptoms — that aren't ...

    www.aol.com/neurologists-reveal-15-subtle...

    During a prodrome period, the Mayo Clinic and American Migraine Foundation say you might experience: Gastrointestinal changes, such as diarrhea or constipation. Food cravings, especially for sweet ...