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Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. [1] ORN occurs most commonly in the mouth during the treatment of head and neck cancer, and can arise over 5 years after radiation. [2]
Current recommendations are for a 2-month drug holiday prior to dental surgery for those who are at risk (intravenous drug therapy, greater than 4 years of by-mouth drug therapy, other factors that increase risk such as steroid therapy). [7] It usually develops after dental treatments involving exposure of bone or trauma, but may arise ...
Pain, inflammation of the surrounding soft tissue, secondary infection or drainage may or may not be present. The development of lesions is most frequent after invasive dental procedures, such as extractions, and is also known to occur spontaneously. There may be no symptoms for weeks or months, until lesions with exposed bone appear. [5]
Radiographs examinations are indicated for any retained root tips, impacted teeth, bony pathology and impacted teeth to minimise post denture insertion discomfort. The degree of maxillary sinus pneumatization, and the position of the inferior alveolar canal and mental foramina are important as well to avoid impingement of denture on these vital ...
Socket preservation or alveolar ridge preservation (ARP) [32] is a procedure to reduce bone loss after tooth extraction to preserve the dental alveolus (tooth socket) in the alveolar bone. At the time of extraction a platelet rich fibrin (PRF) [ 33 ] membrane containing bone growth enhancing elements is placed in the wound or a graft material ...
Researchers found that radiotherapy with either chemotherapy or the hormone drug tamoxifen after surgery does reduce the risk of the disease returning in the subsequent 10 years.
The Wall Street Journal ran a story (in 1989 or after) titled "The Radium Water Worked Fine until His Jaw Came Off". [7] Stories such as that of the Radium Girls and Eben Byers's death went public and due to public pressure and outrage, the Food and Drug Administration banned most radiation-based patent medicines in 1932. [8]
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