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Meralgia paresthetica or meralgia paraesthetica is pain or abnormal sensations in the outer thigh not caused by injury to the thigh, but by injury to a nerve which provides sensation to the lateral thigh. Meralgia paresthetica is a specific instance of nerve entrapment. [5] The nerve involved is the lateral femoral cutaneous nerve (LFCN).
Lateral femoral cutaneous neuralgia, often known as Meralgia Paresthetica, involves neuropathic pain on the outer thigh. The use of a nerve decompression or neurectomy to treat nerve pain along the lateral femoral cutaneous nerve is a firmly established surgical treatment.
This causes meralgia paraesthetica (Bernhardt-Roth syndrome). [2] [5] This may be diagnosed with ultrasound, which changes the morphology of the nerve. [1] Changes can include general enlargement, [1] and a hypoechoic appearance. [3]
A large meta-analysis found that the placebo effect in acute migraine treatments was greatly reduced when the treatment outcome was "pain-free" (9% of patients) compared to "improved" (30% of patients). [36] Studies that have compared migraine surgery to a control group have found similarly low placebo cure rates, both at 4%. [32] [33]
Immunoglobulin and steroids are the first line choices for treatment. [citation needed] In severe cases of CIDP, when second-line immunomodulatory drugs are not efficient, autologous hematopoietic stem cell transplantation (HSCT) is sometimes performed. The treatment may induce long-term remission even in severe treatment-refractory cases of CIDP.
First line treatments are certain antidepressants (tricyclic antidepressants and serotonin–norepinephrine reuptake inhibitors), and anticonvulsants (pregabalin and gabapentin). [26] [27] Opioid analgesics are recognized as useful agents but are not recommended as first line treatments. [27] A broader range of treatments are used in specialist ...
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