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For many antidepressants, this risk is highest during the first few weeks and months of treatment. ... or are breastfeeding. Once prescribed, escitalopram may take some time to start working. Don ...
The use of SSRIs for the treatment of PPD is not a contraindication for breastfeeding. While antidepressants are excreted in breastmilk, the concentrations recorded in breastmilk are very low. [131] [132] Extensive research has shown that the use of SSRI's by women who are lactating is safe for the breastfeeding infant/child.
Breastfeeding is associated with improved social and emotional health and development of the child. [1] The breastfeeding activity induces calming and analgesic effects in the infant. During this activity, their heart and metabolic rates decrease and their sensitivity to pain is reduced. [16]
Fluoxetine taken during pregnancy is associated with a significant increase in congenital heart defects in newborns. [12] [13] It has been suggested that fluoxetine therapy may be continued during breastfeeding if it was used during pregnancy or if other antidepressants were ineffective. [14]
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism.
Nortriptyline may cause problems if taken during pregnancy. [8] Use during breastfeeding appears to be relatively safe. [7] It is a tricyclic antidepressant (TCA) and is believed to work by altering levels of serotonin and norepinephrine. [8] Nortriptyline was approved for medical use in the United States in 1964. [8]
Most of the weight gain caused by antidepressants is mild, with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs) per year on average.
While the rate of side effects appears similar compared to other SSRIs and SNRIs, antidepressant discontinuation syndrome may occur more often. [9] [10] Use in pregnancy is not recommended, while use during breastfeeding is relatively safe. [11] It is believed to work by blocking the reuptake of the chemical serotonin by neurons in the brain. [7]