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The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter. They are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of ...
Meckel nerve endings are most numerous beneath the ridges of the fingertips which make up fingerprints, and less so in the palms and forearm. [citation needed] They can be found at a depth of 900 µm in human fingertips. [4] In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair ...
The neural crest is a ridge-like structure that is formed transiently between the epidermal ectoderm and neural plate during vertebrate development. Neural crest cells originate from this structure through the epithelial-mesenchymal transition, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, dentin, peripheral and enteric ...
Gray's FIG. 726 – Lateral surface of left cerebral hemisphere, viewed from the side Gray's Fig. 727 – Medial surface of left cerebral hemisphere. In neuroanatomy, a gyrus (pl.: gyri) is a ridge on the cerebral cortex.
In neuroanatomy, a sulcus (Latin: "furrow"; pl.: sulci) is a shallow depression or groove in the cerebral cortex.One or more sulci surround a gyrus (pl. gyri), a ridge on the surface of the cortex, creating the characteristic folded appearance of the brain in humans and most other mammals.
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
Brain imaging with MRI reveals a brain with polymicrogyria to have a thin cortex, consistent with the idea that a brain with a thin cortex will have a high level of gyrification. [ 39 ] [ 40 ] A wide array of genes when mutated have been shown to cause Polymicrogyria in humans, ranging from mTORopathies (e.g. AKT3) to channelopathies (sodium ...