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  2. GABAA receptor - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor

    The ionotropic GABA A receptor protein complex is also the molecular target of the benzodiazepine class of tranquilizer drugs. Benzodiazepines do not bind to the same receptor site on the protein complex as does the endogenous ligand GABA (whose binding site is located between α- and β-subunits), but bind to distinct benzodiazepine binding sites situated at the interface between the α- and ...

  3. GABAA receptor positive allosteric modulator - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor_positive...

    In pharmacology, GABA A receptor positive allosteric modulators, also known as GABAkines or GABA A receptor potentiators, [1] are positive allosteric modulator (PAM) molecules that increase the activity of the GABA A receptor protein in the vertebrate central nervous system. GABA is a major inhibitory neurotransmitter in the central nervous system.

  4. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

  5. The #1 Nutrient to Help You Sleep When You’re Traveling ...

    www.aol.com/1-nutrient-help-sleep-traveling...

    It also activates the sleep-regulating neurotransmitter gamma-aminobutyric acid (GABA), which slows brain activity and calms the nervous system. That’s not all.

  6. GABA receptor - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor

    The most common GABA receptor SNPs do not correlate with deleterious health effects in many cases, but do in a few. One significant example of a deleterious mutation is the major association between several GABA receptor gene polymorphisms and schizophrenia.

  7. Allopregnanolone - Wikipedia

    en.wikipedia.org/wiki/Allopregnanolone

    It is made from pregnenolone, and is a positive allosteric modulator of the action of γ-aminobutyric acid (GABA) at GABA A receptor. [10] Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABA A receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant ...