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Autologous stem cell transplants are used more often to treat lymphoma, but this may not be an option if the person's lymphoma has metastasized to their bone marrow or blood. Allogeneic stem cell transplants have side effects that can make it hard for the patient to tolerate the treatment. [ 39 ]
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.
Severe suppression of the bone marrow, heightened vulnerability to infections, gastrointestinal toxicity, and more systemic problems were among the possible side effects. Autologous Stem Cell Transplantation (ASCT), which involves the collection and storage of a patient's own stem cells prior to the administration of HDC, plays a vital role in ...
Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people. [2] It can be also used as an Assisted reproductive technology to improve the reproductive outcomes. In a first step the bone marrow derived stem cells are mobilized.
The approach used in the clinical trial also requires both the transplant and stem cell donation to occur within a two-week period, which can be a significant burden on patients, donors and health ...
Elivaldogene autotemcel is a form of autologous hematopoietic stem cell therapy where ... side effects between 60 days and 1 year after treatment include pyrexia (9% ...
Motixafortide is a hematopoietic stem cell mobilizer and a CXCR4 antagonist. [1] It is given by subcutaneous injection. [1] The most common side effects include injection site reactions, pruritus, flushing, and back pain. [3] Motixafortide was approved for medical use in the United States in September 2023. [3] [4] [5]
Obecabtagene autoleucel, sold under the brand name Aucatzyl, is an anti-cancer medication used for the treatment of acute lymphoblastic leukemia. [1] [2] It is a CD19-directed genetically modified autologous T-cell immunotherapy.
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